Two in U.K. Suffer Allergic Reaction to Pfizer’s Covid-19 Vaccine

LONDON—Two of the first people vaccinated in the U.K. on Tuesday with the Pfizer Inc. -BioNTech SE shot responded adversely to the injection, the country’s National Health Service said, prompting the regulator to issue new guidance warning those with a history of significant allergic reactions against having the inoculation.

“Both are recovering well,” said Stephen Powis, national medical director for the NHS.

The two people are NHS workers, part of the first tranche to receive the vaccine on Tuesday in line with front-line staff having initial access, including those with existing health conditions. Both carried adrenaline auto-injectors to deal with their allergies.

The U.K. is the first Western country to authorize a Covid-19 vaccine and on Tuesday began its vaccination program with priority recipients including health-care staff, people over 80 years old and residents and staff in nursing homes. The NHS said thousands of people received the shot on the first day of the rollout.

The chief executive of the Medical and Health products Regulatory Agency, the body that last week gave the go-ahead for the Pfizer-BioNTech vaccination to be rolled out across the U.K., said that on Tuesday evening the regulator examined two cases of allergic reactions that hadn’t been a feature of the extensive clinical trials of the vaccine.

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